{"id":964,"date":"2020-12-23T01:05:03","date_gmt":"2020-12-23T01:05:03","guid":{"rendered":"http:\/\/region20.herbzinser64.com\/dir\/science03\/?p=964"},"modified":"2020-12-23T01:05:03","modified_gmt":"2020-12-23T01:05:03","slug":"the-external-tragic-expressions-and-message-formats-of-internal-biology-conflicts-with-social-engineering-policy","status":"publish","type":"post","link":"http:\/\/region20.herbzinser64.com\/dir\/science03\/2020\/12\/23\/the-external-tragic-expressions-and-message-formats-of-internal-biology-conflicts-with-social-engineering-policy\/","title":{"rendered":"The EXTERNAL tragic expressions and message formats of  INTERNAL biology conflicts with social engineering policy"},"content":{"rendered":"<p class=\"c2\"><span class=\"c24\">RD-blog-number-2192 by Herb Zinser<\/span><\/p>\n<p class=\"c2 c41\">\n<h3 id=\"h.933wutcmzop8\" class=\"c48\"><span class=\"c40 c42 c31 c69\">The<br \/>\nEXTERNAL tragic expressions and message formats of<\/p>\n<p>INTERNAL biology conflicts with social engineering policy<\/span><\/h3>\n<p class=\"c2 c41\">\n<h2 class=\"c2\"><span class=\"c4 c17\" style=\"color: #ff0000;\">The SOS global response SIGNALS for Oslo, Norway<\/span><\/h2>\n<p class=\"c2\"><span class=\"c4 c31 c67\">The modern social science wars expressed by the atoms and proteins of humanoid participants &#8212;&gt; protein actors in the Theater of Intellectual War.<\/span><\/p>\n<p class=\"c2 c41\">\n<p class=\"c2 c41\">\n<p class=\"c2\"><span class=\"c4\">SOS<\/span><span class=\"c38 c71 c75\">\u00a0Response\u00a0<\/span><span class=\"c38\">\u00e0<\/span><span class=\"c24\">\u00a0the living EARTH cell \u00a0and its geography surface with its \u00a0living cities and institutions \u00a0&#8230;.often \u00a0reflects the INTERNAL biology cell wars . \u00a0Below, are genetics\/ molecular cell biology descriptions from \u00a0university and corporate labs. \u00a0Using that data we can see some \u00a0expressions of cell anger &#8230;&#8230;&#8230;..those expressions use the EARTH humans as vehicles\/ as messengers\/ as actors &#8230;&#8230;that perform EXTERNAL displays of anger \u00a0&#8230;following Nature&#8217;s cellular war instructions.<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<h3 id=\"h.9pl051fl1xyx\" class=\"c33\"><span class=\"c40 c31 c57 c61\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/SOS_response&amp;sa=D&amp;ust=1608689026078000&amp;usg=AOvVaw2pnQ4wBAdcmmce76VwioWA\">SOS response<\/a><\/span><span class=\"c34 c31\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/SOS_response&amp;sa=D&amp;ust=1608689026078000&amp;usg=AOvVaw2pnQ4wBAdcmmce76VwioWA\">\u00a0&#8211; Wikipedia, the free encyclopedia<\/a><\/span><\/h3>\n<p class=\"c13\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c13\"><span class=\"c4 c18\">en.wikipedia.org\/wiki\/<\/span><span class=\"c4 c14\">SOS<\/span><span class=\"c4 c18\">_<\/span><span class=\"c14 c4\">response<\/span><span class=\"c40 c42 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/webcache.googleusercontent.com\/search?q%3Dcache:X52bDo7tgX0J:en.wikipedia.org\/wiki\/SOS_response%2Bsos%2Bresponse%26cd%3D1%26hl%3Den%26ct%3Dclnk%26gl%3Dus&amp;sa=D&amp;ust=1608689026079000&amp;usg=AOvVaw3fboiSbXNt5YikmK2xD2l9\">Cached<\/a><\/span><span class=\"c4\">\u00a0&#8211;<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/www.google.com\/search?hl%3Den%26rlz%3D1W1ACEW_enUS375%26q%3Drelated:en.wikipedia.org\/wiki\/SOS_response%2Bsos%2Bresponse%26tbo%3D1%26sa%3DX%26ei%3Dfj_iT_nEDMLy2QXzl53fCw%26ved%3D0CB0QHzAA&amp;sa=D&amp;ust=1608689026080000&amp;usg=AOvVaw38DhLSDHgcRDSObgkcS_nI\">\u00a0<\/a><\/span><span class=\"c40 c42 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/www.google.com\/search?hl%3Den%26rlz%3D1W1ACEW_enUS375%26q%3Drelated:en.wikipedia.org\/wiki\/SOS_response%2Bsos%2Bresponse%26tbo%3D1%26sa%3DX%26ei%3Dfj_iT_nEDMLy2QXzl53fCw%26ved%3D0CB0QHzAA&amp;sa=D&amp;ust=1608689026080000&amp;usg=AOvVaw38DhLSDHgcRDSObgkcS_nI\">Similar<\/a><\/span><\/p>\n<p class=\"c13\"><span class=\"c4\">The\u00a0<\/span><span class=\"c4 c31\">SOS response<\/span><span class=\"c4\">\u00a0is a global response to DNA damage in which the cell cycle is arrested and DNA repair and mutagenesis are induced. The system involves\u00a0<\/span><span class=\"c49 c4 c31\">&#8230;<\/span><\/p>\n<p class=\"c13\"><span class=\"c4 c6\">\u00a0<\/span><\/p>\n<p class=\"c13\"><span class=\"c40 c4 c57\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/SOS_response%23Discovery&amp;sa=D&amp;ust=1608689026081000&amp;usg=AOvVaw2LYyFHqW-iBX2_qRvneEXZ\">Discovery<\/a><\/span><span class=\"c4\">\u00a0&#8211;<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/SOS_response%23Mechanism&amp;sa=D&amp;ust=1608689026081000&amp;usg=AOvVaw3gW5Wy-Fj4m-2wzhv2GBDc\">\u00a0<\/a><\/span><span class=\"c40 c4 c57\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/SOS_response%23Mechanism&amp;sa=D&amp;ust=1608689026081000&amp;usg=AOvVaw3gW5Wy-Fj4m-2wzhv2GBDc\">Mechanism<\/a><\/span><span class=\"c4\">\u00a0&#8211;<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/SOS_response%23Antibiotic_resistance&amp;sa=D&amp;ust=1608689026082000&amp;usg=AOvVaw2iwcGfiID2eqDywhXUI4Zj\">\u00a0<\/a><\/span><span class=\"c40 c4 c57\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/SOS_response%23Antibiotic_resistance&amp;sa=D&amp;ust=1608689026082000&amp;usg=AOvVaw2iwcGfiID2eqDywhXUI4Zj\">Antibiotic resistance<\/a><\/span><span class=\"c4\">\u00a0&#8211;<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/SOS_response%23Genotoxicity_Testing&amp;sa=D&amp;ust=1608689026082000&amp;usg=AOvVaw1zFvLrq1Tr7C_FIvIst89U\">\u00a0<\/a><\/span><span class=\"c40 c4 c57\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/SOS_response%23Genotoxicity_Testing&amp;sa=D&amp;ust=1608689026082000&amp;usg=AOvVaw1zFvLrq1Tr7C_FIvIst89U\">Genotoxicity Testing<\/a><\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c13\"><span class=\"c4\">The SOS response has been proposed as a model for bacterial evolution of certain types of<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Antibiotic_resistance&amp;sa=D&amp;ust=1608689026083000&amp;usg=AOvVaw3Mjankp2Un_26JlozydOb_\">\u00a0<\/a><\/span><span class=\"c16 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Antibiotic_resistance&amp;sa=D&amp;ust=1608689026083000&amp;usg=AOvVaw3Mjankp2Un_26JlozydOb_\">antibiotic resistance<\/a><\/span><span class=\"c4\">.<\/span><span class=\"c3\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/SOS_response%23cite_note-0&amp;sa=D&amp;ust=1608689026084000&amp;usg=AOvVaw2V9kivPSkT--L3X-HYHO3n\">[1]<\/a><\/span><\/p>\n<p class=\"c13\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c13\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c4\">The\u00a0<\/span><span class=\"c4 c31\">SOS response<\/span><span class=\"c4\">\u00a0is a global response to DNA damage in which the<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Cell_cycle&amp;sa=D&amp;ust=1608689026084000&amp;usg=AOvVaw2CpaejYW2MUTfM6jnAY033\">\u00a0<\/a><\/span><span class=\"c16 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Cell_cycle&amp;sa=D&amp;ust=1608689026085000&amp;usg=AOvVaw1SSWuFWG0wYQl4-beS-MIK\">cell cycle<\/a><\/span><span class=\"c4\">\u00a0is arrested and<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/DNA_repair&amp;sa=D&amp;ust=1608689026085000&amp;usg=AOvVaw0QsZsvgd5msF6gYAmNgYFw\">\u00a0<\/a><\/span><span class=\"c16 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/DNA_repair&amp;sa=D&amp;ust=1608689026085000&amp;usg=AOvVaw0QsZsvgd5msF6gYAmNgYFw\">DNA repair<\/a><\/span><span class=\"c4\">\u00a0and mutagenesis are induced. The system involves the<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/RecA&amp;sa=D&amp;ust=1608689026086000&amp;usg=AOvVaw3Rv-nHF9xKkIedKMdeNJJt\">\u00a0<\/a><\/span><span class=\"c16 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/RecA&amp;sa=D&amp;ust=1608689026086000&amp;usg=AOvVaw3Rv-nHF9xKkIedKMdeNJJt\">RecA<\/a><\/span><span class=\"c4\">\u00a0protein (Rad51 in eukaryotes). The RecA protein, stimulated by single-stranded DNA, is involved in the inactivation of the<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/LexA&amp;sa=D&amp;ust=1608689026086000&amp;usg=AOvVaw1geqoGibsoqT747IXKqW1V\">\u00a0<\/a><\/span><span class=\"c16 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/LexA&amp;sa=D&amp;ust=1608689026087000&amp;usg=AOvVaw0XNmYUhwy2T9mCaJPamR-I\">LexA<\/a><\/span><span class=\"c6 c4\">\u00a0repressor thereby inducing the response. It is an error-prone repair system.<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00e0Translation of \u00a0 the \u00a0EARH LAB social science illness of cities and their citizen nonsense<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">Word SIGNAL: \u00a0SOS response is a global response<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">Keywords: \u00a0 \u00a0 \u00a0 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0SOS \u2026\u2026\u2026\u2026\u2026\u2026.bal<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">Example: Sammy SOSA \u00a0\u2026\u2026\u2026\u2026\u2026.bal &#8211;&gt; Base Bal(l) \u00a0and Baltimore sports<\/span><\/p>\n<p class=\"c2\"><span class=\"c4\">\u00a0<\/span><span class=\"c4 c31\">Samuel Peralta &#8220;Sammy&#8221; Sosa<\/span><span class=\"c4\">\u00a0(born November 12, 1968) is a<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Dominican_Republic&amp;sa=D&amp;ust=1608689026088000&amp;usg=AOvVaw30rImIkhgg5n4kvVldyZcu\">\u00a0<\/a><\/span><span class=\"c40 c42 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Dominican_Republic&amp;sa=D&amp;ust=1608689026089000&amp;usg=AOvVaw0UiM3GdlL2rwptvVAU41Lx\">Dominican<\/a><\/span><span class=\"c4\">\u00a0former professional<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Baseball&amp;sa=D&amp;ust=1608689026089000&amp;usg=AOvVaw1Ik12Vs2XzjIuw-f0800kT\">\u00a0<\/a><\/span><span class=\"c40 c42 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Baseball&amp;sa=D&amp;ust=1608689026089000&amp;usg=AOvVaw1Ik12Vs2XzjIuw-f0800kT\">baseball<\/a><\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Right_fielder&amp;sa=D&amp;ust=1608689026090000&amp;usg=AOvVaw24k4doc5xkgewV28rZwOv3\">\u00a0<\/a><\/span><span class=\"c40 c42 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Right_fielder&amp;sa=D&amp;ust=1608689026090000&amp;usg=AOvVaw24k4doc5xkgewV28rZwOv3\">right fielder<\/a><\/span><span class=\"c4\">.\u00a0<\/span><span class=\"c4 c31\">Sosa played with four<\/span><span class=\"c4 c31\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Major_League_Baseball&amp;sa=D&amp;ust=1608689026090000&amp;usg=AOvVaw36H4DSy4A0YB0BRIAbVnAg\">\u00a0<\/a><\/span><span class=\"c40 c4 c31 c42\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Major_League_Baseball&amp;sa=D&amp;ust=1608689026091000&amp;usg=AOvVaw0VxZqKr7yDhRsZvyJF35o7\">Major League Baseball<\/a><\/span><span class=\"c6 c4\">\u00a0teams over his career which spanned from 1989-2007.<\/span><\/p>\n<p class=\"c2\"><span class=\"c4 c31\">Sosa played with four<\/span><span class=\"c4 c31\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Major_League_Baseball&amp;sa=D&amp;ust=1608689026091000&amp;usg=AOvVaw0VxZqKr7yDhRsZvyJF35o7\">\u00a0<\/a><\/span><span class=\"c40 c42 c4 c31\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Major_League_Baseball&amp;sa=D&amp;ust=1608689026092000&amp;usg=AOvVaw0svFKubkA4cO3GaQay2aY_\">Major League Baseball<\/a><\/span><\/p>\n<p class=\"c2\"><span class=\"c4 c31\">Sos \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0layer \u00a0with four<\/span><span class=\"c4 c31\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Major_League_Baseball&amp;sa=D&amp;ust=1608689026092000&amp;usg=AOvVaw0svFKubkA4cO3GaQay2aY_\">\u00a0<\/a><\/span><span class=\"c40 c42 c4 c31\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Major_League_Baseball&amp;sa=D&amp;ust=1608689026093000&amp;usg=AOvVaw311fKsGZ1NxLSZbjAXhsB_\">Major Nitrogenous \u00a0 Bases<\/a><\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c4 c31\">Sos box &#8230;.<\/span><span class=\"c4\">\u00a0in the operator region for those genes<\/span><span class=\"c4 c31 c49\">\u00a0 applied genetics<\/span><\/p>\n<p class=\"c2 c41\">\n<p class=\"c2\"><span class=\"c49 c4 c31\">SOSA \u00a0in the DNA nucleotide batter&#8217;s box<\/span><\/p>\n<table class=\"c54\">\n<tbody>\n<tr class=\"c15\">\n<td class=\"c28\" colspan=\"2\" rowspan=\"1\">\n<p class=\"c26\"><img decoding=\"async\" title=\" ... Shift+R improves the quality of this image. CTRL+F5 reloads the whole page.\" src=\"http:\/\/region20.herbzinser64.com\/dir\/science03\/wp-content\/uploads\/sites\/4\/2020\/12\/img_5fe297c03396b.png\" alt=\"undefined\" \/><\/p>\n<\/td>\n<\/tr>\n<tr class=\"c50\">\n<td class=\"c30\" colspan=\"2\" rowspan=\"1\">\n<p class=\"c43\"><span class=\"c40 c10 c42 c31\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Right_fielder&amp;sa=D&amp;ust=1608689026094000&amp;usg=AOvVaw1HNuR1Sp2jK27tR10GXruo\">Right fielder<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n<tr class=\"c65\">\n<td class=\"c28\" colspan=\"2\" rowspan=\"1\">\n<p class=\"c26\"><span class=\"c10 c31\">Born:<\/span><span class=\"c6 c10\">\u00a0November 12, 1968 (age 43)<\/span><\/p>\n<p class=\"c26\"><span class=\"c40 c10 c42\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/San_Pedro_de_Macor%25C3%25ADs,_Dominican_Republic&amp;sa=D&amp;ust=1608689026096000&amp;usg=AOvVaw2x4dRsqzETbk_6OtNix9rH\">San Pedro de Macor\u00eds, Dominican Republic<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n<tr class=\"c50\">\n<td class=\"c8\" colspan=\"1\" rowspan=\"1\">\n<p class=\"c26\"><span class=\"c10 c31\">Batted:<\/span><span class=\"c6 c10\">\u00a0Right<\/span><\/p>\n<\/td>\n<td class=\"c8\" colspan=\"1\" rowspan=\"1\">\n<p class=\"c26\"><span class=\"c10 c31\">Threw:<\/span><span class=\"c6 c10\">\u00a0Right<\/span><\/p>\n<\/td>\n<\/tr>\n<tr class=\"c50\">\n<td class=\"c28 c58\" colspan=\"2\" rowspan=\"1\">\n<p class=\"c26\"><span class=\"c10 c31\">MLB debut<\/span><\/p>\n<\/td>\n<\/tr>\n<tr class=\"c50\">\n<td class=\"c28\" colspan=\"2\" rowspan=\"1\">\n<p class=\"c26\"><span class=\"c6 c10\">June 16, 1989 for the Texas Rangers<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p class=\"c2\"><span class=\"c4\">\u00a0<\/span><span class=\"c40 c55 c4 c60\">\u00a0Major league career<\/span><\/p>\n<ul class=\"c56 lst-kix_bu7xbtjtign8-0 start\">\n<li class=\"c2 c20\"><span class=\"c40 c42 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Sammy_Sosa%23Texas_Rangers.2C_Chicago_White_Sox_.281989.E2.80.931991.29&amp;sa=D&amp;ust=1608689026098000&amp;usg=AOvVaw3G5lqc8NzwC1119YXwCaqa\">2.1 Texas Rangers, Chicago White Sox (1989\u20131991)<\/a><\/span><\/li>\n<li class=\"c2 c20\"><span class=\"c40 c42 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Sammy_Sosa%23Chicago_Cubs_.281992.E2.80.932004.29&amp;sa=D&amp;ust=1608689026099000&amp;usg=AOvVaw3rLyFKqOmA8MQVhVaflvSC\">2.2 Chicago Cubs (1992\u20132004)<\/a><\/span><\/li>\n<li class=\"c2 c20\"><span class=\"c40 c42 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Sammy_Sosa%23Baltimore_Orioles_and_year_off_.282005.E2.80.932006.29&amp;sa=D&amp;ust=1608689026099000&amp;usg=AOvVaw1kUtGphyRjLDWx-Z8yjmDW\">2.3 Baltimore Orioles and year off (2005\u20132006)<\/a><\/span><\/li>\n<li class=\"c2 c20\"><span class=\"c40 c42 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Sammy_Sosa%23Recent_years_.282007.E2.80.932009.29&amp;sa=D&amp;ust=1608689026100000&amp;usg=AOvVaw2U7DD1BKhl5TAIc9ZYnc-x\">2.4 Recent years (2007\u20132009)<\/a><\/span><\/li>\n<\/ul>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<h2 id=\"h.l9r342zbro56\" class=\"c9\"><span class=\"c31 c52 c61\">\u00a0<\/span><span class=\"c19\">\u00a0<\/span><\/h2>\n<h2 id=\"h.5zo1yus13h1k\" class=\"c9\"><span class=\"c23\">\u00a0Mechanism<\/span><\/h2>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c4\">During normal growth, the SOS genes are negatively regulated by LexA<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Repressor_protein&amp;sa=D&amp;ust=1608689026101000&amp;usg=AOvVaw2j8AEFr8M1awXfH5LYoKQt\">\u00a0<\/a><\/span><span class=\"c16 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Repressor_protein&amp;sa=D&amp;ust=1608689026101000&amp;usg=AOvVaw2j8AEFr8M1awXfH5LYoKQt\">repressor protein<\/a><\/span><span class=\"c4\">\u00a0dimers. Under normal conditions, LexA binds to a 20-bp consensus sequence (the<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/SOS_box&amp;sa=D&amp;ust=1608689026101000&amp;usg=AOvVaw3cJ6o5Xj9-H_FdovGISZrh\">\u00a0<\/a><\/span><span class=\"c16 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/SOS_box&amp;sa=D&amp;ust=1608689026101000&amp;usg=AOvVaw3cJ6o5Xj9-H_FdovGISZrh\">SOS box<\/a><\/span><span class=\"c4\">) in the operator region for those genes. Some of these SOS genes are expressed at certain levels even in the repressed state, according to the affinity of LexA for their SOS box. Activation of the SOS genes occurs after DNA damage by the accumulation of single stranded (ssDNA) regions generated at replication forks, where<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/DNA_polymerase&amp;sa=D&amp;ust=1608689026102000&amp;usg=AOvVaw0UesvWpTla0c10vzjxor6h\">\u00a0<\/a><\/span><span class=\"c16 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/DNA_polymerase&amp;sa=D&amp;ust=1608689026102000&amp;usg=AOvVaw0UesvWpTla0c10vzjxor6h\">DNA polymerase<\/a><\/span><span class=\"c4\">\u00a0is blocked. RecA forms a filament around these ssDNA regions in an ATP-dependent fashion, and becomes activated. The activated form of RecA interacts with the LexA repressor to facilitate the LexA repressor&#8217;s self-cleavage from the operator.<\/span><span class=\"c3\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/SOS_response%23cite_note-2&amp;sa=D&amp;ust=1608689026102000&amp;usg=AOvVaw0brZzHucDlR-MHVq7xQ9sb\">[3]<\/a><\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00e0Translation words: \u00a0 protein dimmers \u00a0\u2026.. with the proteins of physics professors and the theory of 11-dimensions of DIMER string theory \u00a0\u2026\u2026..with Margaret Mead nuclear family anthropology LAB \u00a0dimer specimen \u2026.Jessie Dimmick&#8230;.. who received an 11-year prison sentence of behalf of atomic social \u00a0engineering experiments \u2026.and \u00a0is \u00a0testing \u00a0the \u00a0secret CLOSED and MYOPIC communications of universities.<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c29 c63\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00e0Translation of \u00a0 the \u00a0above regarding Runway 26<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<table class=\"c54\">\n<tbody>\n<tr class=\"c62\">\n<td class=\"c46\" colspan=\"1\" rowspan=\"1\">\n<p class=\"c13 c39\"><span class=\"c6 c4\">Word SIGNAL: \u00a0LexA represor proteins \u00a0\u2026..SOS box \u2026polymerase\u2026. RecA<\/span><\/p>\n<p class=\"c13 c39\"><span class=\"c6 c4\">Keywords: \u00a0 \u00a0 \u00a0 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0LexA \u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026.SOS \u2026\u2026\u2026\u2026\u2026erase \u2026\u2026RecA<\/span><\/p>\n<p class=\"c13 c39\"><span class=\"c6 c4\">Example: \u00a0Lexington Airport\u2026..SOS emergency\u2026.erase COMAIR\u2026 wRECk \u00a0Airplane<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">SOS box \u00e0 the airplane is like a rectangular box of aluminum metal,etc<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><img decoding=\"async\" title=\"File:SOS response antibiotic resistance.png ... Shift+R improves the quality of this image. CTRL+F5 reloads the whole page.\" src=\"http:\/\/region20.herbzinser64.com\/dir\/science03\/wp-content\/uploads\/sites\/4\/2020\/12\/img_5fe297c13d02e.png\" alt=\"\" \/><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">Above, \u00a0INTERNAL \u00a0&#8230;&#8230;. DNA structure, flowcharts and DNA alphabet runways<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">Below, the Mirror of Miroslav RADMAN who discovered SOS repsonse.<\/span><\/p>\n<p class=\"c2\"><span class=\"c4\">Analysis of the<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Cockpit_voice_recorder&amp;sa=D&amp;ust=1608689026105000&amp;usg=AOvVaw0l49ifaItTWa-wuciVAuX2\">\u00a0<\/a><\/span><span class=\"c40 c42 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Cockpit_voice_recorder&amp;sa=D&amp;ust=1608689026105000&amp;usg=AOvVaw0l49ifaItTWa-wuciVAuX2\">cockpit voice recorder<\/a><\/span><span class=\"c4\">\u00a0(CVR) indicated the aircraft was cleared to take off from Runway 22, a 7,003 feet (2,135 m) strip used by most airline traffic at Lexington.<\/span><span class=\"c27\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Comair_Flight_191%23cite_note-NTSB-prelim-4&amp;sa=D&amp;ust=1608689026106000&amp;usg=AOvVaw1rl0qsibI3PwE6b5oRWZfW\">[5]<\/a><\/span><span class=\"c6 c4\">\u00a0Instead, after confirming &#8220;Runway two-two&#8221;, Captain Jeffrey Clay taxied onto Runway 26,<\/span><\/p>\n<p class=\"c7\">\n<p class=\"c13\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c13\"><img decoding=\"async\" title=\" ... Shift+R improves the quality of this image. CTRL+F5 reloads the whole page.\" src=\"http:\/\/region20.herbzinser64.com\/dir\/science03\/wp-content\/uploads\/sites\/4\/2020\/12\/img_5fe297c1e7e06.jpg\" alt=\"undefined\" \/><\/p>\n<p class=\"c13\"><img \/><\/p>\n<p class=\"c13\"><span class=\"c6 c4\">Approximate paths at Blue Grass Airport (picture before airport construction done weeks before the crash):<\/span><\/p>\n<p class=\"c13\"><span class=\"c6 c4\">Desired path via Runway 22<\/span><\/p>\n<p class=\"c13\"><span class=\"c6 c4\">Actual path via Runway 26, ending at approximate crash site.<\/span><\/p>\n<p class=\"c13\"><span class=\"c4 c31\">X<\/span><span class=\"c6 c4\">\u00a0marks the closed taxiway<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">Analysis \u00a0of the LexA and the \u00a0English alphabet &#8230;the LEXICON of Runway 26 letters. \u00a0Thus the TRUE NATURE of the communications mix-up at the Lexington Airport \u00a0&#8230;&#8230;&#8230;. was Nature&#8217;s way of getting out a signal about 26 letters of Lex A = Lexicon Alpabet words . Hence, Nature&#8217;s military brain cells \u00a0managed to push button in the brains of the airport and airline personnel. \u00a0 Thus &#8230;as William Shakespeare stated<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">&#8221; The WORLD is a stage and we are the \u00a0biochemistry players&#8221;.<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">Below words: \u00a0pool of \u00a0LexA<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">Translate: Computer Earth system 370 with I\/O \u00a0port and terminal \u00e0 air.PORT \u00a0TERMINAL and the data record buffer pool of Lexington, Americans..<\/span><\/p>\n<p class=\"c2 c41\">\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c4\">Once the\u00a0<\/span><span class=\"c31 c53\">pool of LexA<\/span><span class=\"c4\">\u00a0decreases, repression of the SOS genes goes down according to the level of LexA affinity for the SOS boxes. Operators that bind LexA weakly are the first to be fully expressed. In this way LexA can sequentially activate different mechanisms of repair. Genes having a weak SOS box (such as lexA, recA, uvrA, uvrB, and uvrD) are fully induced in response to even weak SOS-inducing treatments. Thus the first SOS repair mechanism to be induced is<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Nucleotide_excision_repair&amp;sa=D&amp;ust=1608689026107000&amp;usg=AOvVaw0V5xJ9bOLEoTFHTnUpRDpa\">\u00a0<\/a><\/span><span class=\"c16 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Nucleotide_excision_repair&amp;sa=D&amp;ust=1608689026108000&amp;usg=AOvVaw3EPB0cypGjrRz-Og7KyyBj\">nucleotide excision repair<\/a><\/span><span class=\"c6 c4\">\u00a0(NER), whose aim is to fix DNA damage without commitment to a full-fledged SOS response.<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c4\">If, however, NER does not suffice to fix the damage, the LexA concentration is further reduced, so the expression of genes with stronger LexA boxes (such as sulA, umuD, umuC &#8211; these are expressed late) is induced. SulA stops<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Cell_division&amp;sa=D&amp;ust=1608689026108000&amp;usg=AOvVaw08-DcwKLITPgY-cV6xynrx\">\u00a0<\/a><\/span><span class=\"c16 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Cell_division&amp;sa=D&amp;ust=1608689026108000&amp;usg=AOvVaw08-DcwKLITPgY-cV6xynrx\">cell division<\/a><\/span><span class=\"c4\">\u00a0by binding to FtsZ, the initiating protein in this process. This causes<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Filamentation&amp;sa=D&amp;ust=1608689026109000&amp;usg=AOvVaw2Gq3wxO-GdYgG2vbfRACOD\">\u00a0<\/a><\/span><span class=\"c16 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Filamentation&amp;sa=D&amp;ust=1608689026109000&amp;usg=AOvVaw2Gq3wxO-GdYgG2vbfRACOD\">filamentation<\/a><\/span><span class=\"c6 c4\">, and the induction of UmuDC-dependent mutagenic repair. As a result of these properties, some genes may be partially induced in response to even endogenous levels of DNA damage, while other genes appear to be induced only when high or persistent DNA damage is present in the cell.<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<h2 id=\"h.exc46j6k17sh\" class=\"c9\"><span class=\"c23\">\u00a0Antibiotic resistance<\/span><\/h2>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c4\">Recent research has shown that the SOS pathway may be essential in the acquisition of bacterial mutations which lead to<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Antibiotic_resistance&amp;sa=D&amp;ust=1608689026110000&amp;usg=AOvVaw2Q32HsTh1bDXN-Qhcg_AuH\">\u00a0<\/a><\/span><span class=\"c16 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Antibiotic_resistance&amp;sa=D&amp;ust=1608689026110000&amp;usg=AOvVaw2Q32HsTh1bDXN-Qhcg_AuH\">resistance<\/a><\/span><span class=\"c4\">\u00a0to some antibiotic drugs.<\/span><span class=\"c3\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/SOS_response%23cite_note-Lee-3&amp;sa=D&amp;ust=1608689026110000&amp;usg=AOvVaw1F77JEiGfNMhRO9BWKABZJ\">[4]<\/a><\/span><span class=\"c4\">\u00a0The increased rate of mutation during the SOS response is caused by three low-fidelity<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/DNA_polymerase&amp;sa=D&amp;ust=1608689026111000&amp;usg=AOvVaw3WmdcLBkc3MmXnx1k1csEv\">\u00a0<\/a><\/span><span class=\"c16 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/DNA_polymerase&amp;sa=D&amp;ust=1608689026111000&amp;usg=AOvVaw3WmdcLBkc3MmXnx1k1csEv\">DNA polymerases<\/a><\/span><span class=\"c4\">:<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Pol_II&amp;sa=D&amp;ust=1608689026111000&amp;usg=AOvVaw0PJA5whapkKoit4Fmn_L8N\">\u00a0<\/a><\/span><span class=\"c16 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Pol_II&amp;sa=D&amp;ust=1608689026111000&amp;usg=AOvVaw0PJA5whapkKoit4Fmn_L8N\">Pol II<\/a><\/span><span class=\"c4\">,<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/w\/index.php?title%3DPol_IV%26action%3Dedit%26redlink%3D1&amp;sa=D&amp;ust=1608689026112000&amp;usg=AOvVaw3cjxEjS7MqNxGZfWZ4uZlZ\">\u00a0<\/a><\/span><span class=\"c16 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/w\/index.php?title%3DPol_IV%26action%3Dedit%26redlink%3D1&amp;sa=D&amp;ust=1608689026112000&amp;usg=AOvVaw3cjxEjS7MqNxGZfWZ4uZlZ\">Pol IV<\/a><\/span><span class=\"c4\">\u00a0and<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/w\/index.php?title%3DPol_V%26action%3Dedit%26redlink%3D1&amp;sa=D&amp;ust=1608689026112000&amp;usg=AOvVaw2J1VyJyC2d0xQYKPkl9V0k\">\u00a0<\/a><\/span><span class=\"c16 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/w\/index.php?title%3DPol_V%26action%3Dedit%26redlink%3D1&amp;sa=D&amp;ust=1608689026113000&amp;usg=AOvVaw0HhHdU15XtieQLE8bHa0i9\">Pol V<\/a><\/span><span class=\"c4\">.<\/span><span class=\"c3\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/SOS_response%23cite_note-Lee-3&amp;sa=D&amp;ust=1608689026113000&amp;usg=AOvVaw3ejwOD-rbIrEcHmDegEDgY\">[4]<\/a><\/span><span class=\"c4\">\u00a0Researchers are now targeting these proteins with the aim of creating drugs that prevent SOS repair. By doing so, the time needed for pathogenic bacteria to evolve antibiotic resistance could be extended, and thus improve the long term viability of some antibiotic drugs.<\/span><span class=\"c3\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/SOS_response%23cite_note-4&amp;sa=D&amp;ust=1608689026113000&amp;usg=AOvVaw3sDCh6tZQE1QSIq7XIkXN3\">[5]<\/a><\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00e0Below ..city testing \u2026 Baltimore region \u00a0<\/span><\/p>\n<h2 id=\"h.887lxhbmkfwe\" class=\"c9\"><span class=\"c23\">Genotoxicity Testing \u00a0&#8211;&gt;<\/span><\/h2>\n<h2 id=\"h.n7kwolj9qt6v\" class=\"c9\"><span class=\"c23\">\u00a0<\/span><\/h2>\n<h2 id=\"h.gbycbm1mqqby\" class=\"c36\"><span class=\"c40 c31 c74\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/www.google.com\/search?hl%3Den%26rlz%3D1W1ACEW_enUS375%26biw%3D1366%26bih%3D543%26q%3Dbaltimore%2Bmd%2Bpopulation%26sa%3DX%26ei%3Dy1PiT4XHM4eO2wWJpNipCw%26ved%3D0CLcBEOgT&amp;sa=D&amp;ust=1608689026114000&amp;usg=AOvVaw3F3mP9E_UMxvxbzRJK-7Px\">Population<\/a><\/span><span class=\"c19\">: 620,961 (2010)<\/span><\/h2>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<h3 id=\"h.g3pnlcmo01ra\" class=\"c33\"><span class=\"c34 c31\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/baltimore&amp;sa=D&amp;ust=1608689026115000&amp;usg=AOvVaw0z_sRKxzFEzhQ8UZ1NyGRT\">The\u00a0<\/a><\/span><span class=\"c31 c32\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/baltimore&amp;sa=D&amp;ust=1608689026115000&amp;usg=AOvVaw0z_sRKxzFEzhQ8UZ1NyGRT\">Baltimore<\/a><\/span><span class=\"c34 c31\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/baltimore&amp;sa=D&amp;ust=1608689026115000&amp;usg=AOvVaw0z_sRKxzFEzhQ8UZ1NyGRT\">\u00a0Sun | Breaking news, sports, weather and traffic in &#8230;<\/a><\/span><span class=\"c1\">\u00a0<\/span><span class=\"c14 c59\">www.baltimoresun.com\/<\/span><span class=\"c40 c42 c59 c31\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/www.baltimoresun.com\/Cached&amp;sa=D&amp;ust=1608689026115000&amp;usg=AOvVaw3Pt7PkqTVkX3Mvl5BiqqqX\">Cached<\/a><\/span><span class=\"c1\">\u00a0&#8211;<\/span><span class=\"c1\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/www.google.com\/search?hl%3Den%26rlz%3D1W1ACEW_enUS375%26biw%3D1366%26bih%3D543%26q%3Drelated:www.baltimoresun.com\/%2Bbaltimore%26tbo%3D1%26sa%3DX%26ei%3Dy1PiT4XHM4eO2wWJpNipCw%26ved%3D0CDUQHzAF&amp;sa=D&amp;ust=1608689026115000&amp;usg=AOvVaw0qTMzsDOvSCAcuer7FvWNz\">\u00a0<\/a><\/span><span class=\"c40 c42 c31 c59\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/www.google.com\/search?hl%3Den%26rlz%3D1W1ACEW_enUS375%26biw%3D1366%26bih%3D543%26q%3Drelated:www.baltimoresun.com\/%2Bbaltimore%26tbo%3D1%26sa%3DX%26ei%3Dy1PiT4XHM4eO2wWJpNipCw%26ved%3D0CDUQHzAF&amp;sa=D&amp;ust=1608689026116000&amp;usg=AOvVaw2V8Z7W7vabqwhNFG00O8db\">Similar<\/a><\/span><\/h3>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c13\"><span class=\"c4\">News, business, sports, arts, lifestyle, opinion, archives, classifieds, food, travel and subscription and advertising information for the\u00a0<\/span><span class=\"c4 c31 c52\">Baltimore<\/span><span class=\"c4\">\u00a0region can be\u00a0<\/span><span class=\"c49 c4 c31\">&#8230;<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<h2 id=\"h.sy0zwd7xe471\" class=\"c9\"><span class=\"c19\">\u00a0<\/span><\/h2>\n<p class=\"c13\"><span class=\"c49 c4 c31\">Baltimore<\/span><\/p>\n<p class=\"c13\"><img decoding=\"async\" title=\" ... Shift+R improves the quality of this image. CTRL+F5 reloads the whole page.\" src=\"http:\/\/region20.herbzinser64.com\/dir\/science03\/wp-content\/uploads\/sites\/4\/2020\/12\/img_5fe297c2bbf1f.gif\" alt=\"undefined\" \/><\/p>\n<p class=\"c25\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c13\"><span class=\"c4\">Baltimore is the largest city in the U.S. state of Maryland. It is located in the central area of the state along the tidal portion of the Patapsco River, an arm of the Chesapeake Bay.<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Baltimore&amp;sa=D&amp;ust=1608689026118000&amp;usg=AOvVaw13HEcEF6GDGYpR-kMINIw1\">\u00a0<\/a><\/span><span class=\"c40 c64\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Baltimore&amp;sa=D&amp;ust=1608689026118000&amp;usg=AOvVaw13HEcEF6GDGYpR-kMINIw1\">Wikipedia<\/a><\/span><\/p>\n<p class=\"c37\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c13\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<table class=\"c54\">\n<tbody>\n<tr class=\"c73\">\n<td class=\"c21\" colspan=\"1\" rowspan=\"1\">\n<p class=\"c13\"><span class=\"c40 c4 c31\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/www.google.com\/search?hl%3Den%26rlz%3D1W1ACEW_enUS375%26biw%3D1366%26bih%3D543%26q%3Dbaltimore%2Bmd%2Bfounded%26sa%3DX%26ei%3Dy1PiT4XHM4eO2wWJpNipCw%26ved%3D0CK8BEOgT&amp;sa=D&amp;ust=1608689026119000&amp;usg=AOvVaw2zWk-eXIsDgZ5lLt7cOHyg\">Founded<\/a><\/span><span class=\"c4 c31\">:\u00a0<\/span><span class=\"c6 c4\">July 30, 1729<\/span><\/p>\n<p class=\"c13\"><span class=\"c4 c31 c40\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/www.google.com\/search?hl%3Den%26rlz%3D1W1ACEW_enUS375%26biw%3D1366%26bih%3D543%26q%3Dbaltimore%2Bmd%2Barea%26sa%3DX%26ei%3Dy1PiT4XHM4eO2wWJpNipCw%26ved%3D0CLEBEOgT&amp;sa=D&amp;ust=1608689026120000&amp;usg=AOvVaw0DHmW1wT_gD5TN8GEddN4p\">Area<\/a><\/span><span class=\"c4 c31\">:\u00a0<\/span><span class=\"c6 c4\">92 sq miles (239 km\u00b2)<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p class=\"c25\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c13\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c13\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c13\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c13\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c13\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c13\"><span class=\"c6 c4\">Overview of the use of the SOS response for genotoxicity testing<\/span><\/p>\n<p class=\"c2\"><span class=\"c4\">\u00a0<\/span><img decoding=\"async\" title=\"File:Genotoxic Damage.png ... Shift+R improves the quality of this image. CTRL+F5 reloads the whole page.\" src=\"http:\/\/region20.herbzinser64.com\/dir\/science03\/wp-content\/uploads\/sites\/4\/2020\/12\/img_5fe297c3b4a13.png\" alt=\"\" \/><\/p>\n<p class=\"c13\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00e0Translation of \u00a0 below \u2026.<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">Escherichia coli \u00a0 \u00e0 E coli<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">Escherichia = E + sch + er \u00a0= Education school error<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">Different classes &#8211;&gt; the school classroom shootings .<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<h3 id=\"h.9rmozie91gaq\" class=\"c33\"><span class=\"c31 c34\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/www.usnews.com\/news\/national\/articles\/2008\/02\/15\/timeline-of-school-shootings&amp;sa=D&amp;ust=1608689026121000&amp;usg=AOvVaw0vP8bno5eLHayRJH4y6vE4\">Timeline of School Shootings &#8211; US News and World Report<\/a><\/span><\/h3>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c13\"><span class=\"c4 c12\">Feb 15, 2008 \u2013\u00a0<\/span><span class=\"c4\">Clarification: An earlier version of this\u00a0<\/span><span class=\"c4 c31\">timeline<\/span><span class=\"c4\">\u00a0omitted several significant\u00a0<\/span><span class=\"c4 c31\">shootings<\/span><span class=\"c4\">\u00a0that have taken place at colleges and other\u00a0<\/span><span class=\"c4 c31\">schools<\/span><span class=\"c4\">\u00a0since\u00a0<\/span><span class=\"c49 c4 c31\">&#8230;<\/span><\/p>\n<ul class=\"c56 lst-kix_jwcfzi4jf4f2-0 start\">\n<li class=\"c2 c20\"><span class=\"c34 c31\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/School_shooting&amp;sa=D&amp;ust=1608689026123000&amp;usg=AOvVaw3yoE2i1EQy_PEohHM8gQm1\">School shooting &#8211; Wikipedia, the free encyclopedia\n<p><\/a><\/span><span class=\"c4\"><\/p>\n<p><\/span><span class=\"c4 c18\">en.wikipedia.org\/wiki\/<\/span><span class=\"c14 c4\">School<\/span><span class=\"c4 c18\">_<\/span><span class=\"c14 c4\">shooting<\/span><span class=\"c40 c42 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/webcache.googleusercontent.com\/search?q%3Dcache:Ft4wQaXbdb0J:en.wikipedia.org\/wiki\/School_shooting%2BTimeline%2Bgrammer%2Bschool%2Bshootings%26cd%3D2%26hl%3Den%26ct%3Dclnk%26gl%3Dus&amp;sa=D&amp;ust=1608689026124000&amp;usg=AOvVaw04M3N1mENS2ZzFVmRV8E2w\">Cached<\/a><\/span><span class=\"c4\">\u00a0&#8211;<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/www.google.com\/search?hl%3Den%26rlz%3D1W1ACEW_enUS375%26biw%3D1366%26bih%3D543%26q%3Drelated:en.wikipedia.org\/wiki\/School_shooting%2BTimeline%2Bgrammar%2Bschool%2Bshootings%26tbo%3D1%26sa%3DX%26ei%3DXFXiT-T1EuSa2AXczuDRCw%26ved%3D0CBUQHzAB&amp;sa=D&amp;ust=1608689026124000&amp;usg=AOvVaw2VDervUAuwIKbQlI_pfA-5\">\u00a0<\/a><\/span><span class=\"c40 c42 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/www.google.com\/search?hl%3Den%26rlz%3D1W1ACEW_enUS375%26biw%3D1366%26bih%3D543%26q%3Drelated:en.wikipedia.org\/wiki\/School_shooting%2BTimeline%2Bgrammar%2Bschool%2Bshootings%26tbo%3D1%26sa%3DX%26ei%3DXFXiT-T1EuSa2AXczuDRCw%26ved%3D0CBUQHzAB&amp;sa=D&amp;ust=1608689026125000&amp;usg=AOvVaw2hskQat7AjvAOty3QDsJEE\">Similar<br \/>\n<\/a><\/span><span class=\"c4\">\u00a0A school\u00a0<\/span><span class=\"c4 c31\">shooting<\/span><span class=\"c4\">\u00a0is an incident in which gun violence occurs at an educational institution.\u00a0<\/span><span class=\"c4 c31\">&#8230;..<\/span><span class=\"c4\">\u00a0<\/span><span class=\"c4 c31\">Timeline<\/span><span class=\"c4\">\u00a0of School\u00a0<\/span><span class=\"c4 c31\">Shootings<\/span><span class=\"c6 c4\">\u00a0&#8211; US News and World Report&#8221;.<\/p>\n<p><\/span><\/li>\n<li class=\"c2 c20\"><span class=\"c34 c31\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/tamilhelp.wordpress.com\/2008\/05\/13\/timeline-us-shooting-sprees-history-of-school-shootings\/&amp;sa=D&amp;ust=1608689026125000&amp;usg=AOvVaw3gZMo7M8z3q8hliXGFjJVB\">Timeline: US shooting sprees \u2013 History of school shootings \u00ab\n<p><\/a><\/span><\/li>\n<\/ul>\n<p class=\"c2\"><span class=\"c6 c4\">Thus the E coli shootings \u2026\u2026.. like Virginia TECH English department \u00a0and the grammar \/ high school shootings<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c4\">In\u00a0<\/span><span class=\"c4 c52\">Escherichia coli<\/span><span class=\"c4\">,\u00a0<\/span><span class=\"c31 c61\">different classes<\/span><span class=\"c4\">\u00a0of DNA-damaging agents can initiate the SOS response, as described above. Taking advantage of an operon fusion placing the<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Lac_operon&amp;sa=D&amp;ust=1608689026126000&amp;usg=AOvVaw1uclncFXel3IGzqKLsO5Q7\">\u00a0<\/a><\/span><span class=\"c16 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Lac_operon&amp;sa=D&amp;ust=1608689026126000&amp;usg=AOvVaw1uclncFXel3IGzqKLsO5Q7\">lac operon<\/a><\/span><span class=\"c4\">\u00a0(responsible for producing beta-galactosidase, a protein which degrades lactose) under the control of an SOS-related protein, a simple colorimetric assay for<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Genotoxicity&amp;sa=D&amp;ust=1608689026127000&amp;usg=AOvVaw1dClon92hDfkSk8lcqbDlH\">\u00a0<\/a><\/span><span class=\"c16 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Genotoxicity&amp;sa=D&amp;ust=1608689026127000&amp;usg=AOvVaw1dClon92hDfkSk8lcqbDlH\">genotoxicity<\/a><\/span><span class=\"c4\">\u00a0is possible. A lactose analog is added which to the bacteria, which is degraded by beta-galactosidase, producing a colored compound which can be measured quantitatively through<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Spectrophotometry&amp;sa=D&amp;ust=1608689026127000&amp;usg=AOvVaw2elCKfgYlvapT98iQsYt4X\">\u00a0<\/a><\/span><span class=\"c4 c16\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Spectrophotometry&amp;sa=D&amp;ust=1608689026127000&amp;usg=AOvVaw2elCKfgYlvapT98iQsYt4X\">spectrophotometry<\/a><\/span><span class=\"c6 c4\">). The degree of color development is an indirect measure of the beta-galactosidase produced, which itself is directly related to the amount of DNA damage.<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00e0Above\u2026lac operon at Lac La Belle, Oconomowoc, Wisconsin region with \u00a0Mark and Gloria Totzke.<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00e0Above spectrophotometry with \u00a0the \u00a0tatoo \u00a0optical signal of seemen (seaman) Richard Speck (year 1966) \u00a0in \u00a0the Chicago spectrum murders<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c4\">The\u00a0<\/span><span class=\"c4 c52\">E. coli<\/span><span class=\"c4\">\u00a0are further modified in order to have a number of mutations including a uvrA mutation which renders the strain deficient in excision repair, increasing the response to certain DNA-damaging agents, as well as an rfa mutation, which renders the bacteria lipopolysaccharide-deficient, allowing better diffusion of certain chemicals into the cell in order to induce the SOS response.<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/SOS_response%23cite_note-5&amp;sa=D&amp;ust=1608689026129000&amp;usg=AOvVaw3QvOMxxYHCsY70W3iYCniH\">\u00a0<\/a><\/span><span class=\"c3\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/SOS_response%23cite_note-5&amp;sa=D&amp;ust=1608689026129000&amp;usg=AOvVaw3QvOMxxYHCsY70W3iYCniH\">[6]<\/a><\/span><span class=\"c4\">\u00a0Commercial kits which measures the primary response of the\u00a0<\/span><span class=\"c4 c31\">E. coli<\/span><span class=\"c4\">\u00a0cell to genetic damage are available and may be highly correlated with the<\/span><span class=\"c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Ames_Test&amp;sa=D&amp;ust=1608689026130000&amp;usg=AOvVaw1QP5Q1UlU0et1e8F61B_vS\">\u00a0<\/a><\/span><span class=\"c16 c4\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/Ames_Test&amp;sa=D&amp;ust=1608689026130000&amp;usg=AOvVaw1QP5Q1UlU0et1e8F61B_vS\">Ames Test<\/a><\/span><span class=\"c4\">\u00a0for certain materials.<\/span><span class=\"c3\"><a class=\"c0\" href=\"https:\/\/www.google.com\/url?q=http:\/\/en.wikipedia.org\/wiki\/SOS_response%23cite_note-6&amp;sa=D&amp;ust=1608689026130000&amp;usg=AOvVaw2rjCb1AU94Of0FmwC6Ea0P\">[7]<\/a><\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c13 c70\"><span class=\"c4 c51\">\u00a0Thus the SOS = S \u00a0+ OS &#8211;&gt; Shootings OSLO &#8230;&#8230;ought pay attention to Nature&#8217;s message EVENT at UTOEYA.<\/span><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<p class=\"c13 c45\"><span class=\"c51 c68 c4 c72\">\u00a0<\/span><\/p>\n<p class=\"c2\"><span class=\"c6 c4\">\u00a0<\/span><\/p>\n<div class=\"edit-link\"><a class=\"post-edit-link\" href=\"\">edit<\/a><\/div>","protected":false},"excerpt":{"rendered":"<p>RD-blog-number-2192 by Herb Zinser The EXTERNAL tragic expressions and message formats of INTERNAL biology conflicts with social engineering policy The SOS global response SIGNALS for Oslo, Norway The modern social science wars expressed by the atoms and proteins of humanoid participants &#8212;&gt; protein&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-964","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"http:\/\/region20.herbzinser64.com\/dir\/science03\/wp-json\/wp\/v2\/posts\/964","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/region20.herbzinser64.com\/dir\/science03\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/region20.herbzinser64.com\/dir\/science03\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/region20.herbzinser64.com\/dir\/science03\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/region20.herbzinser64.com\/dir\/science03\/wp-json\/wp\/v2\/comments?post=964"}],"version-history":[{"count":1,"href":"http:\/\/region20.herbzinser64.com\/dir\/science03\/wp-json\/wp\/v2\/posts\/964\/revisions"}],"predecessor-version":[{"id":970,"href":"http:\/\/region20.herbzinser64.com\/dir\/science03\/wp-json\/wp\/v2\/posts\/964\/revisions\/970"}],"wp:attachment":[{"href":"http:\/\/region20.herbzinser64.com\/dir\/science03\/wp-json\/wp\/v2\/media?parent=964"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/region20.herbzinser64.com\/dir\/science03\/wp-json\/wp\/v2\/categories?post=964"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/region20.herbzinser64.com\/dir\/science03\/wp-json\/wp\/v2\/tags?post=964"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}